Coronavirus

Coronavirus Mutations, Variants, Epitopes, and Vaccine Efficacy

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This article provides an overview of virus mutations, the current variants from the UK and South Africa, how the immune system works on pathogen proteins, and whether all this has implications on the efficacy of the current vaccines.

Mutations

Mutations are a fact of life for all living beings. Viruses, due to many reasons (generation rate in hours, infecting millions of cells, ...), have a very fast mutation rate. That is just what goes on.

China Will Be Using Anal Swabs for Coronavirus, But Not For Everyone

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Users on social media have been sharing news that China is using Anal Swabs for detecting Coronavirus infections. While this is true, it seems that this will not be applied to everyone being tested.

These anal swabs are soaked in saline, and inserted into the anus and rotated.

If you see this France24 article, you will notice this part:

COVID-19 SARS-CoV-2 Coronavirus Receptors For Cell Entry And Pathogenicity

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SARS-CoV-2, the Coronavirus that causes COVID-19 and is responsible for the 2020 pandemic, is known to enter cells via the ACE2 receptor (see this video on the Renin-Angiotensin system).

In addition to ACE2, there are other receptors that either facilitate entry into cells (making the virus more infectious) or increase its pathogenicity (causing more severe symptoms).

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